Table 1.
Clinical and demographic features of human cohort.
| Groups | Sex | Mean Age (Year) ± SD | Mean Plasma Viral RNA Copies/mL ± SD | Mean CSF Viral RNA Copies/mL ± SD | Average of CD4+ T-Cell Cells/µL ± SD | HIV-1 RNA Copies/g of Tissue | HIV-1 DNA Copies/g of Tissue | HIV-1 iDNA Copies/g of Tissue | Neurocognitive Impairment | HIV Encephalitis (HIVE) |
|---|---|---|---|---|---|---|---|---|---|---|
| HIV[ − ] (n = 10) | 9M/1F | 48.5 ± 8.1 | ND * | ND * | Not available | ND * | ND * | ND * | Not impaired | No HIVE |
| HIV[+] (n = 10) | 9M/1F | 50 ± 5.3 | 1.33 × 105
± 338,060 |
1.62 × 104
± 1.95 × 104 |
88.8 ± 95 | 5.64 × 103 | 3.57 × 104 | 8.38 × 103 | Not impaired | No HIVE |
| HIV[+]/HAND (n = 10) | 7M/3F | 42 ± 9.5 | 2.25 × 105 ± 2.47 × 105 |
1.45 × 103
± 2.08 × 103 |
88.2 ± 136 | 3.59 × 104 | 4.78 × 104 | 9.74 × 103 | Impaired | No HIVE |
| HIV[+]/HIVE (n = 10) | 9M/1F | 39 ± 5.6 | 4.44 × 105
± 3.61 × 105 |
1.66 × 106
± 1.24 × 106 |
47 ± 32 | 1.05 × 105 | 1.65 × 105 | 3.71 × 104 | Impaired | With HIVE |
* Not Detected.