Table 2.
Demographic and clinical data/characteristics (unit) of the HCC group (n = 39), liver cirrhosis group (n = 40) participants compared to each other.
| Group (n) | |||
|---|---|---|---|
| Data/Characteristics (Unit) | HCC (39) | LC (40) | p Value |
| Gender (M/F) | 27/12 | 28/12 | NS |
| Age (years) | 61.0 (56.0–67.0) | 58.5 (54.25–65.0) | NS |
| BMI (Kg/m2) | 29.0 (27.0–31.0) | 29.9 (27.55–33.2) | NS |
| D.M (Yes/No) | 15/24 | 24/16 | NS |
| s. Insulin (mIU/L) | 25.0 (15.7–42.5) | 13.5 (5.98–20.37) | 0.001 * |
| Insulin resistance (Yes/No) | 28/11 | 25/15 | 0.001 * |
| AST (U/L) | 77.0 (62–105.0) | 72.0 (62.0–78.0) | NS |
| ALT (U/L) | 51.0 (42.0–65.0) | 57.0 (50.0–63.7) | NS |
| Total Bilirubin (mg/dl) | 1.2 (0.9–2.0) | 1.5 (1.0–3.07) | NS |
| Direct Bilirubin (mg/dl) | 0.70 (0.40–1.2) | 0.8 (0.4–1.95) | NS |
| ALP (U/L) | 110 (82.0–155.0) | 120 (99.8–132.8) | NS |
| GGT (U/L) | 60 (53.0–77.0) | 67 (55.3–83.5) | NS |
| TC (mg/dl) | 162 (122.0–220) | 147 (112-181) | NS |
| TAG (mg/dl) | 133 (94.0–193.0) | 115 (76.8–147) | NS |
| HDL-C (mg/dl) | 34 (26.0–40.0) | 36.5 (30.5–41.75) | NS |
| TAG/HDL-C ratio | 4.1 (2.6–6.7) | 3.3 (2.34–4.59) | NS |
| INR | 1.2 (1.1–1.37) | 1.5 (1.30–2.06) | <0.001 * |
Data are median (inter quartile range (1st–3rd quartile)), statistics were computed using SPSS software, Mann–Whitney test was used (for non-parametric data). p indicates comparison between HCC and liver cirrhosis groups; * statistical significance p-value < 0.05; NS, non-significant. ALT, alanine aminotransferase; AST, aspartate aminotransferase; AFP, alpha fetoprotein; BMI, body mass index; DM, diabetes mellitus; HCC, hepatocellular carcinoma; HDL, high-density lipoprotein; GGT, gamma glutamyl transferase; LC, liver cirrhosis; s. albumin, serum albumin; s. insulin, serum insulin, TC, total cholesterol; TAG, triacylglycerol.