Table 6.
CHCV-G4 Patients (n = 79) miRs-Fold Change | ||||||||
---|---|---|---|---|---|---|---|---|
hsa-miR-21-5p | hsa-miR-155-5p | hsa-miR-192-5p | hsa-miR-199a-5p | |||||
Data/Characteristics (Unit) | r | p-Value | r | p-Value | r | p-Value | r | p-Value |
Age (Years) | 0.004 | NS | −0.004 | NS | −0.060 | NS | −0.054 | NS |
BMI (kg/m2) | 0.103 | NS | 0.059 | NS | −0.124 | NS | −0.222 | 0.050 * |
s. Insulin (mIU/L) | 0.334 | 0.01 * | 0.203 | NS | −0.001 | NS | −0.125 | NS |
AFP (ng/mL) | 0.534 | <0.001 * | 0.371 | 0.001 * | −0.092 | NS | −0.023 | NS |
AST (U/L) | 0.104 | NS | −0.001 | NS | 0.070 | NS | 0.03 | NS |
ALT (U/L) | −0.172 | NS | −0.138 | NS | 0.114 | NS | −0.068 | NS |
ALP (U/L) | −0.263 | 0.019 * | −0.163 | NS | −0.043 | NS | 0.069 | NS |
GGT (U/L) | −0.144 | NS | −0.120 | NS | 0.106 | NS | 0.145 | NS |
TAG (mg/dL) | 0.241 | 0.033 * | 0.180 | NS | −0.144 | NS | 0.133 | NS |
TC (mg/dL) | 0.235 | 0.037 * | 0.120 | NS | −0.230 | 0.042 * | 0.075 | NS |
HDL-C (mg/dL) | −0.110 | NS | −0.064 | NS | −0.062 | NS | −0.064 | NS |
TAG/HDL-C | 0.195 | NS | 0.115 | NS | −0.085 | NS | 0.111 | NS |
PLR | −0.045 | NS | 0.137 | NS | −0.119 | NS | 0.298 | 0.008 * |
Number of liver masses | −0.027 | NS | −0.038 | NS | 0.010 | NS | −0.018 | NS |
Insulin resistance | 0.303 | 0.02 * | 0.103 | NS | 0.140 | NS | −0.090 | NS |
Spearman correlation coefficient (r) was calculated using SPSS software. * Significant correlation at p < 0.05 level (2-tailed); NS, non-significant; LC, liver cirrhosis; ALT, alanine aminotransferase; AST, aspartate aminotransferase; AFP, alpha-fetoprotein; BMI, body mass index; DM, diabetes mellitus; HCC, hepatocellular carcinoma; HDL, high-density lipoprotein; GGT, gamma-glutamyl transferase; LC, liver cirrhosis; PLR, platelet lymphocyte ratio; NLR, neutrophil–lymphocyte ratio; s. insulin, serum insulin; TC, total cholesterol; TAG, triacylglycerol.