Table 8.
Logistic regression analysis using hsa-miR-21-5p, has-miR-155-5p, hsa-miR-192-5p, and hsa-miR199a-5p expression level fold change and their ratios as predictors of HCV-mediated HCC development from liver cirrhosis (n = 79) after adjustment for confounders (age, BMI, RBS, lipids).
| 95% C.I. | ||||
|---|---|---|---|---|
| Variables (Unit) | p Value | OR | Lower | Upper |
| hsa-miR-21-5p | 0.002 * | 1.189 | 1.063 | 1.329 |
| hsa-miR-155-5p | NS | 0.984 | 0.881 | 1.100 |
| hsa-miR-192-5p | NS | 1.009 | 0.851 | 1.196 |
| hsa-miR-199a-5p | NS | 0.836 | 0.594 | 1.177 |
| hsa-miR-21-5p/hsa-miR-199a-5p | NS | 1.0 | 1.0 | 1.0 |
| hsa-miR-155-5p/hsa-miR-199a-5p | NS | 1.0 | 0.99 | 1.0 |
| Age (years) | 0.027 * | 1.132 | 1.014 | 1.263 |
| BMI (Kg/m2) | 0.02 * | 0.746 | 0.583 | 0.955 |
| TAG/HDL-C | NS | 1.180 | 0.927 | 1.501 |
| TAG | NS | 1.002 | 0.988 | 1.016 |
| TC | NS | 1.004 | 0.992 | 1.015 |
| RBS | NS | 0.993 | 0.981 | 1.005 |
* Significant p-value < 0.05. BMI, body mass index; C.I., confidence interval; HCC, hepatocellular carcinoma; HDL, high-density lipoprotein; OR, odds ratio; RBS, random blood sugar; TAG, triacyl glycerol; TC, total cholesterol.