Table 3.
Intra-day and inter-day average (avg) precision and accuracy assessed at four concentration levels (LLOQ, LQC, MQC and HQC) for five times (intra-day) in three different analytical runs (inter-day).
| Intra-Day (n = 5) | Inter-Day (n = 3) | ||||||
|---|---|---|---|---|---|---|---|
| QC Levels | Nominal Conc. (μg/mL) |
Avg Conc. (μg/mL) | Avg Precision (CV%) | Avg Accuracy (Bias%) | Avg Conc. (μg/mL) | Avg Precision (CV%) | Avg Accuracy (Bias%) |
| LLOQ | 0.125 | 0.130 | 12.3 | 4.1 | 0.136 | 13.5 | 7.2 |
| Low | 7 | 6.55 | 10.2 | 9.1 | 6.41 | 7.6 | 9.3 |
| Medium | 70 | 68.3 | 8.4 | 5.8 | 64.9 | 7.0 | 7.9 |
| High | 280 | 252.4 | 11.6 | 9.9 | 241.7 | 13.0 | 13.7 |