Table 5.
New drugs for the treatment of drug-resistant tuberculosis.
| Generic Name | Brand Name | Company | Approval | CAS Number | Clinical Indications | Molecular Mechanism |
|---|---|---|---|---|---|---|
| Bedaquiline (59) | Sirturo | Janssen Therapeutics | 2012 | 843663-66-1 | Multidrug-resistant tuberculosis | Adenosine triphosphate synthase inhibitor |
| Delamanid (60) | Deltyba | Otsuka | 2014 | 681492-22-8 | Multidrug-resistant tuberculosis | Cell wall synthesis inhibitor |
| Pretomanid (61) | Dovprela | Mylan | 2019 | 187235-37-6 | Multidrug-resistant tuberculosis | Cell wall synthesis inhibitor |