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. 2023 Feb 5;24(4):3147. doi: 10.3390/ijms24043147

Figure 4.

Figure 4

Representative response surfaces where the PDNP size was kept constant, and the other factors were varied. (A) CCC design-based model output visualized, showing a clear optimum. (B) BBD-based model output visualized, with no clear optimum being present in the investigated design space. (C) Revised BBD-based model output visualized, now showing a clear optimum.