Table 1.

IC₅₀ values ± SD [µM] of compounds 2, 3, 12, and 18 obtained in enzymatic fluorescence-based assay with recombinant β-lactamases VIM-1, IMP-7, and NMD-1. All measurements were performed in at least triplicates.

Compound	VIM-1	IMP-7	NDM-1
12	1.3 ± 0.02	0.27 ± 0.018	1.9 ± 0.27
2	0.17 ± 0.021	0.36 ± 0.052	4.3 ± 0.44
18	1.3 ± 0.31	0.11 ± 0.021	0.22 ± 0.016
3	0.42 ± 0.024	0.045 ± 0.009	0.13 ± 0.017