Table 5.
Longitudinal association of NP1 with T1D, adjusted for HLA, race/ethnicity, sex and family history of T1D.
| Shared Parameter | HR | Lower CI | Upper CI | p-Value |
|---|---|---|---|---|
| Original NP1 (Average) | 0.54 | 0.22 | 1.333 | 0.1829 |
| Original NP1 (Cumulative) | 0.98 | 0.84 | 1.129 | 0.7310 |
| Simplified NP1 (Average) | 0.52 | 0.22 | 1.240 | 0.1402 |
| Simplified NP1 (Cumulative) | 0.99 | 0.85 | 1.152 | 0.9054 |
The joint Cox PH model of NP1 developed using the reduced rank regression with the genetically adjusted oxylipin profiles as the response variables. HR is for a 1 standard deviation increase in the NP1 score. Upper and lower 85% confidence interval (CI) are displayed.