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Effect of trimetazidine on exercise capacity and right ventricular (RV) morphology. Twenty-seven PAH subjects were randomized and assigned to trimetazidine (TMZ) or placebo for three months and then reallocated to the other study arm. (A) Exercise capacity was determined using 6 min walk distance (6MWD) test. (B) RV morphology was assessed by echocardiography. Data were analyzed using paired t-test. * p < 0.05.
