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. 2023 Feb 5;24(4):3155. doi: 10.3390/ijms24043155

Figure 2.

Figure 2

ZNF385A and ZNF346 are overexpressed in HCC, and their diagnostic potential. (A,B) ZNF385A and ZNF346 mRNA expression in 371 HCCs, and 160 adjacent normal tissues from the TCGA and GTEx databases. (C,D) ZNF385A and ZNF346 mRNA expression in paired tumor and adjacent normal tissues of 50 patients with HCC in TCGA. (E,F) ZNF385A and ZNF346 mRNA expression from the ICGC database. (G) Correlation scatter plot of ZNF385A and ZNF346. (H) Validation of ZNF385A and ZNF346 protein levels in normal liver cell (LO2) and HCC cell (HepG2) via Western blot analysis. (I) ROC curves to test the diagnostic value of ZNF385A and ZNF346. ** p < 0.01; *** p < 0.001.