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. 2023 Feb 2;15(2):501. doi: 10.3390/pharmaceutics15020501

Table 4.

Block-copolymer/surfactant-based formulations for innovative drug delivery applications.

Block-Copolymer Surfactant Drug Use
PDLLA mPEG Paclitaxel Breast cancer
d,l-lactide, glycolide, ε-caprolactone Pluronic F-68 Potentially protein drugs Injectable, sustained release formulation
ABA, A(BA)n, or B(AB)n hydrophilic/hydrophobic block-copolymers PEG Labile peptide and protein drugs, antibiotics, adriamycin, mitomycin, bleomycin, cisplatin, carboplatin, doxorubicin, daunorubicin, 5-fluorouracil, methotrexate, taxol, taxotere, actinomycin D Anticancer, antimicrobial, anti-inflamatory
polycaprolactone (PCL) Pluronic F-68 indocyanine green (ICG) Imaging and photothermal therapy (PTT)