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The effects of rhamnose, rutinose, hesperidin, and hesperetin on IL-6 (A,B) and IL-8 (C,D) production by young or physiologically aged NHDFs, that were cultivated in low-glucose medium, high-glucose medium, and medium supplemented with AGEs. Untreated NHDFs cultivated in these individual media were used as controls. A number of measurements: n = 6. (One-way ANOVA; Dunnett’s multiple comparisons tests were performed using GraphPad Prism).
