Table 2.
Name | Lipinski’s Rules | |||||
---|---|---|---|---|---|---|
MW <500 |
HBA <10 |
HBD ≤5 |
Mlog P ≤4.15 |
Lipinski’s Volations | Bioavailability Score | |
G1 | 516.46 | 8 | 2 | 1.63 | 2 | 0.17 |
G2 | 546.48 | 10 | 0 | 2.31 | 2 | 0.17 |
G3 | 548.46 | 10 | 4 | −0.13 | 2 | 0.17 |
G4 | 548.46 | 10 | 2 | 0.41 | 2 | 0.17 |