Table 1.

Specific and multiple roles of circular RNA in the pathogenesis of myocardial infarction, including cardiomyocyte death, inflammatory infiltration, and fibrosis. They are described in detail in the text.

Name	Expression	Function	Ref.
CircNfix	Upregulated Downregulated	Pro-apoptotic; inhibits angiogenesis	[45,46]
CircACAP2	Upregulated	Pro-apoptotic	[47,48]
CircMFACR	Upregulated	Pro-apoptotic	[49,50]
CircPVT1	Upregulated	Pro-apoptotic	[51]
CircNCX1	Upregulated	Pro-apoptotic	[52]
CircJARID2	Upregulated	Pro-apoptotic	[53]
CircROBO2	Upregulated	Pro-apoptotic	[54]
CircRbms1	Upregulated	Pro-apoptotic	[55,56]
Circ-CBFB	Upregulated	Pro-apoptotic	[57]
Circ-TRRAP	Upregulated	Pro-apoptotic	[58]
Circ-010567	Upregulated	Pro-apoptotic	[59]
Circ-101237	Upregulated	Pro-apoptotic; promotes autophagy	[60]
Circ-0124644	Upregulated	Pro-apoptotic	[61]
Circ-0068655	Upregulated	Pro-apoptotic	[62]
CircSAMD4A	Upregulated	Pro-inflammatory infiltration; pro-apoptotic	[63]
CircHelz	Upregulated	Pro-inflammatory infiltration	[64]
Circ_0060745	Upregulated	Pro-inflammatory infiltration; pro-apoptotic	[65]
CircFASTKD1	Upregulated	Inhibits angiogenesis	[66]
CircPAN3	Upregulated	Promotes autophagy; promotes fibrosis	[67]
CircHIPK3	Upregulated	Promotes collagen deposition; promotes fibrosis	[68,69]
CircPOSTN	Upregulated	Promotes collagen deposition; promotes fibrosis	[70,71]
CircCNEACR	Downregulated	Inhibits programmed necrosis	[20]
CircSamd4	Downregulated	Inhibits apoptosis; inhibits fibrosis	[21]
CircACR	Downregulated	Inhibits autophagy	[42]
CircCDYL	Downregulated	Inducing myocardial regeneration	[72]
CircFndc3b	Downregulated	Inhibits apoptosis; promotes angiogenesis	[41]
CircSNRK	Downregulated	Inhibits apoptosis; promotes angiogenesis	[73]
CircMACF1	Downregulated	Inhibits apoptosis	[74]
Circ_0001206	Downregulated	Inhibits apoptosis	[75]
CircUBXN7	Downregulated	Inhibits apoptosis; inhibits inflammatory infiltration	[76]
CircNFIB	Downregulated	Inhibits fibrosis	[77]