Table 1.
A list of mutagenic base and nucleotide analogs used in lethal mutagenesis of RNA viruses.
| Virus | Family | Mutagenic Base and Nucleotide Analog |
|---|---|---|
| Polio virus | Picornaviridae | Ribavirin, 5-nitrocytidine |
| Dengue virus | Flavivirus | 5-Fluorouracil, ribavirin |
| Zika virus | Flavivirus | Ribavirin, favipiravir |
| Hepatitis C virus | Flaviviridae | Ribavirin, favipiravir |
| Hepatitis E virus | Hepeviridae | Ribavirin |
| SARS-CoV-2 | Coronaviridae | Favipiravir |
| Tobacco mosaic virus | Virgaviridae | 5-fluorouracil |
| Influenza A virus | Orthomyxoviridae | 5-fluorouracil, Ribavirin 5-azacytidine |
| Vesicular stomatitis virus | Rhabdoviridae | 5-fluorouracil |
| Hantaan virus | Hantaviridae | Ribavirin |
| Rift valley fever virus | Phenuiviridae | Favipiravir |
| Ebola virus | Filoviridae | 5-fluorouracil |
| Marburg virus | Filovirade | Favipiravir |