Table 2.
Percentage and absolute amount of lipoprotein subfractions in study participants.
| Controls (n = 49) | NDO (n = 106) | T2DM (n = 62) | |
|---|---|---|---|
| VLDL (%) | 17.69 ± 3.2 | 19.9 ± 4.1 * | 20.8 ± 5.2 § |
| IDL (%) | 26.6 ± 6.3 | 25.3 ± 4 | 24.6 ± 3.9 |
| large LDL (%) | 23.2 ± 6.1 | 28 ± 4.7 * | 26.9 ± 5.4 § |
| small-dense LDL (%) | 0.6 (0–1.9) | 1.15 (0–2.4) | 1.65 (0–3.3) § |
| mean LDL size (nm) | 27.3 (27–27.4) | 27.1 (26.9–27.3) * | 26.9 (26.9–27.3) §,# |
| large HDL (%) | 29 ± 8.7 | 22.9 ± 7 * | 18.9 ± 6.5 §,# |
| intermediate HDL (%) | 50.3 ± 4.6 | 51.1 ± 3.7 | 48.8 ± 4.1 |
| small HDL (%) | 20.7 ± 6.3 | 26 ± 6.8 * | 32.2 ± 7.7 §,# |
| VLDL (mmol/L) | 0.89 ± 0.19 | 1.0 ± 0.24 * | 1.1 ± 0.49 § |
| IDL (mmol/L) | 1.34 ± 0.41 | 1.25 ± 0.30 | 1.23 ± 0.33 |
| large LDL (mmol/L) | 1.17 ± 0.38 | 1.41 ± 0.36 * | 1.33 ± 0.41 |
| small-dense LDL (mmol/L) | 0.032 (0–0.093) | 0.058 (0–0.13) | 0.075 (0–0.185) |
| large HDL (mmol/L) | 0.46 ± 0.26 | 0.30 ± 0.14 * | 0.24 ± 0.12 § |
| intermediate HDL (mmol/L) | 0.73 ± 0.17 | 0.67 ± 0.17 | 0.58 ± 0.14 §,# |
| small HDL (mmol/L) | 0.29 ± 0.07 | 0.34 ± 0.10 * | 0.37 ± 0.10 § |
Abbreviations: HDL, high-density lipoprotein; IDL, intermediate-density lipoprotein; LDL, low-density lipoprotein; NDO, non-diabetic obese patients; T2DM, patients with type 2 diabetes mellitus; VLDL, very-low density lipoprotein. Notes: Data are presented as mean ± SD and analyzed using one-way ANOVA or median (interquartile range) and analyzed using the Kruskal-Wallis H test. * indicates p < 0.05 between controls vs. NDO. § indicates p < 0.05 between controls and T2DM. # indicates a p < 0.05 between NDO and T2DM.