Table 2.
Pathway associated with differentially expressed genes in cumulus cells and oocytes between the plate and gel culture systems.
| Term | Count | p-Value |
|---|---|---|
| Cumulus cells | ||
| ECM-receptor interaction | 24 | 4.49 × 10−9 |
| MAPK signaling pathway | 44 | 1.74 × 10−7 |
| Pathways in cancer | 67 | 1.85 × 10−7 |
| Focal adhesion | 34 | 4.03 × 10−7 |
| Steroid biosynthesis | 10 | 1.45 × 10−6 |
| Arrhythmogenic right ventricular cardiomyopathy | 18 | 4.16 × 10−6 |
| AGE-RAGE signaling pathway in diabetic complications | 20 | 2.25 × 10−5 |
| Rap signaling pathway | 30 | 0.000112 |
| Human papillomavirus infection | 42 | 0.000116 |
| Metabolic pathways | 137 | 0.00015 |
| Oocyte | ||
| Ribosome | 47 | 3.72 × 10−14 |
| Parkinson disease | 57 | 1.79 × 10−10 |
| Huntington disease | 60 | 1.06 × 10−9 |
| Pathways of neurodegeneration—multiple diseases | 80 | 1.38 × 10−9 |
| Coronavirus disease—COVID-19 | 54 | 3.84 × 10−9 |
| Prion disease | 51 | 8.60 × 10−8 |
| Amyotrophic lateral sclerosis | 62 | 1.85 × 10−7 |
| Alzheimer disease | 62 | 1.03 × 10−6 |
| Thermogenesis | 43 | 1.36 × 10−6 |
| Oxidative phosphorylation | 30 | 3.09 × 10−6 |
| Chemical carcinogenesis—reactive oxygen species | 40 | 1.98 × 10−5 |