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Opportunities for therapeutic interventions in restoring or re-establishing gut microbiota balance after dysbiosis. Normobiosis (1) can be altered through quorum sensing disruption (2). In turn, the quorum sensing disruption leads to decrease in bacterial diversity and pathogens proliferation (3), which eventually results in dysbiosis (4). Dysbiosis can be reversed using probiotics, prebiotics, engineered QS systems, or blockers of pathogens’ QS.
