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. 2023 Feb 1;120(6):e2216230120. doi: 10.1073/pnas.2216230120

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Copyright © 2023 the Author(s). Published by PNAS.

This article is distributed under Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND).

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Fig. 1. — (A) Overall structure of GRPR-PD176252, with GRPR in blue cartoons and PD176252 in orange sticks. (B–H) Structural comparisons among GRPR (in blue), AT₁R (in green), and ET_BR (in goldenrod) from the extracellular view (B) and the intracellular view (C), with enlarged views of the conserved P^5.50V(I)^3.40F^6.44 motif (E), D^3.49R^3.50Y^3.51 motif (F), ECL2 (G), and N^7.49P^7.50xx(x)Y^7.54 motif (H).