Table 1.

Challenges encountered by the radiologists during segmentation and solutions used in the database.

Region/Issue	Solution
Cervical lymph nodes not always distinguishable from surrounding tissues	Include cervical lymph nodes whenever possible
Unsharp border between lymphoma and thymic tissue	Exclude thymus from segmentation only when a clear border between lymphoma and thymus is visible; include thymus in segmentation when no clear border is visible
Unsharp borders between lymphoma/liquefactive necrosis and fluid in pericardium and pleural cavities	Try to exclude any pericardial and pleural effusion and include liquefactive necrosis in the segmentation (difficult in some cases)
Abdominal lymph nodes	Do not include in the segmentation