Table 3.

Physicochemical characteristics of studied mucoadhesive buccal films (F1–F3, according to Table 1).

Parameters	Formulation
	F1	F2	F3
pH	6.3 ± 0.33	5.9 ± 0.20	6.8 ± 0.27
Folding endurance	>350	>350	>350
Thickness (mm)	0.37 ± 0.01	0.45 ± 0.02	0.35 ± 0.01
Tensile strength (MPa)	0.232 ± 0.011	0.122 ± 0.012	0.390 ± 0.066
Swelling index (%) at 180 min	11.62 ± 3.54	17.02 ± 2.16	43.47 ± 8.27
Ex vivo bioadhesion time (min)	285 ± 10	225 ± 12	180 ± 17