Fig. 5.

Autonomic defects in TrkA^R685A mice. (A and B) Representative images of ptosis (eyelid droop) in adult TrkA^R685A mice compared to those in littermate controls. Dashed lines indicate height and width of the eye. (Scale bar, 1 mm.) (C) Quantification of ptosis (ratio of height over width of the eye). Results are the mean ± SEM from 13 TrkA^R685A and 7 TrkA^WT mice. ***P < 0.001, t test. (D and E) Dark-adapted TrkA^R685A mice have decreased basal pupil size compared to control littermates. Pupil is outlined in dashed lines. (Scale bar, 1 mm.) (F) Quantification of pupil area. Results are presented as mean ± SEM from 13 TrkA^R685A and 7 TrkA^WT mice. **P < 0.01, t test.