TABLE 5.

V_max/K_m results for bacterial NATs^a

Strain	Vmax/Km (% of control value)
	2-AF	5-ASA	4-ASA	PABA	SMZ
Control strains
DMG100 (human NAT1)	49b	257	193b	465b	2.2 × 10−2b
DMG200 (human NAT2)	1.04b	1.6 × 10−2	5.1 × 10−4b	—b	3.5 × 10−2b
S. enterica serovar Typhimurium YG1024	1.6 × 10−1 (39,480)	ND	—	1.1 × 10−4 (100)	—
S. enterica serovar Typhimurium TA98	4.7 × 10−4 (112)	ND	—	—	—
S. enterica serovar Typhimurium TA1538	2.9 × 10−4 (69)	ND	—	—	—
Study strains
S. enterica serovar Typhimurium 60.62	4.1 × 10−4 (100)	3.8 × 10−3 (100)	—	—	3.2 × 10−5 (100)
E. coli 54.8	4.8 × 10−4 (115)	7.8 × 10−4 (20)	2.9 × 10−5 (100)	—	5.0 × 10−5 (155)
E. coli K-12	1.8 × 10−4 (42)	—	4.2 × 10−5 (140)	—	1.1 × 10−5 (33)
P. aeruginosa	2.6 × 10−2 (6,375)	9.5 × 10−2 (2,470)	1.2 × 10−3 (4,300)	9.1 × 10−4 (845)	—
C. koseri	5.0 × 10−3 (1,200)	6.4 × 10−3 (170)	3.2 × 10−5 (110)	—	7.2 × 10−6 (22)
C. farmeri	2.0 × 10−3 (480)	6.9 × 10−3 (180)	1.1 × 10−5 (37)	—	2.6 × 10−5 (81)
C. freundii	1.4 × 10−3 (330)	1.7 × 10−3 (44)	3.9 × 10−5 (130)	—	—
C. amalonaticus	1.7 × 10−3 (415)	1.4 × 10−3 (37)	—	ND	—
K. rhinoscleromatis	1.4 × 10−3 (335)	ND	—	—	5.8 × 10−5 (180)
K. oxytoca	1.5 × 10−3 (350)	5.0 × 10−3 (130)	—	—	—
M. morganii	2.5 × 10−5 (6)	—	ND	—	—
H. pylori	2.4 × 10−4 (59)	—	—	—	—
S. marcescens	1.3 × 10−4 (31)	ND	—	—	1.3 × 10−6 (4)
Bacteroides sp.	—	ND	—	3.1 × 10−4 (290)	—

^aSee Table 3, footnotes a, b, and c.