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. 2023 Jan 20;11(2):277. doi: 10.3390/microorganisms11020277

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Impact of a 4-week supplementation with the multistrain probiotic on the adherent gut microbiota in Diarrhoea responders (R) and non-responders (NR). (A–C) α-diversity, estimated by the richness (number of observed ASVs) (A), evenness (Pielou’s index) (B) and Shannon’s index (C); (D) principal coordinate analysis (PCoA) of bacterial β-diversity, measured according to the Bray–Curtis distance; (E) bacterial taxonomic profile at the genus level before (V1) and after (V2) supplementation; (F) differential abundance analysis at ASV levels at V1 and V2 in Diarrhoea NR. Only significant data are presented as Log2 of the fold of change (FC) according to DESeq2 analysis. Transcription start sites (TSS).