. 2023 Feb 17;16(2):315. doi: 10.3390/ph16020315

Table 1.

Chelators (including their respective derivatives) and their most suitable radiometal counterparts commonly used in biomedical applications [29]. (CA: Coordinating Atoms; CN: Coordination Number).

Name	CA	CN	Radiometals
DFO; desferrioxamine B	O₆	6	⁸⁹Zr⁴⁺
DTPA; diethylenetriaminepentaacetic acid	N₃O₅	8	¹¹¹In³⁺, ¹⁷⁷Lu³⁺, ^86/90Y³⁺
Pa Family; H2dedpa; 1,2-[[6-(carboxy)-pyridin-2-yl]- methylamino]ethane	N₄O₂	6	^67/68Ga³⁺,¹¹¹In³⁺, ¹⁷⁷Lu³⁺
HOPO; 3,4,3-(LI-1,2-HOPO)	O₈	8	⁸⁹Zr⁴⁺, ²²⁷Th⁴⁺
NOTA; 1,4,7-triazacyclononane-1,4,7- triacetic acid	N₃O₃	6	¹⁷⁷Lu³⁺, ⁶⁴Cu^{2+, 67/68}Ga^{3+, 86/90}Y^{3+, 212/213}Bi³⁺
DOTA; 1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid, maximum	N₄O₄	8	⁶⁴Cu²⁺, ²¹²Pb²⁺, ^212/213Bi³⁺, ¹⁷⁷Lu³⁺, ²²⁵Ac³⁺, ¹¹¹In³⁺, ^44/47Sc³⁺, ^86/90Y³⁺