Table 3.
Cure rate and egg reduction rate stratified by pre-treatment infection intensity and by status of coinfection with other type of STH parasites.
| STH Parasites | N | Number Cured | Cure Rate, % (95% CI) |
WHO Reference for CR |
Mean (SD) | ERR, % | WHO Reference for ERR | |
|---|---|---|---|---|---|---|---|---|
| By pre-treatment infection intensity | ||||||||
| Hookworms | Light | 61 | 59 | 96.7 (96.7–101.2) | ≥95 | 1.77 (11.1) | 97.5 | ≥90 |
| Ascaris lumbricoides | Light | 791 | 758 | 95.8 (94.4–97.2) | ≥95 | 790.68 (5738.7) | 95.5 | ≥95 |
| Moderate or heavy | 273 | 254 | 93.0 (90.0–96.1) | 115.57 (1090.4) | 89.6 | |||
| Trichirus trichiura | Light | 1262 | 241 | 19.1 (16.9–21.3) | ≥50 | 1047.3 (1977.3) | 62.3 | ≥50 |
| Moderate or heavy | 142 | 6 | 4.2 (0.9–7.5) | 217.3 (573.8) | 12.4 | |||
| By coinfection status | ||||||||
| Hookworms | No coinfection | 4 | 4 | 100 | ≥95 | 0 (0) | 100 | ≥90 |
| Coinfection with AL or TT | 57 | 55 | 96.5 (91.7–101.2) | 1.89 (11.5) | 97.4 | |||
| Ascaris lumbricoides | No coinfection | 114 | 112 | 98.2 (95.8–100.6) | ≥95 | 1.47 (13.7) | 99.9 | ≥95 |
| Coinfection with HW or TT | 950 | 900 | 94.7 (93.3–96.2) | 323.3 (3242.7) | 94.5 | |||
| Trichirus trichiura | No coinfection | 438 | 113 | 25.8 (21.7–29.9) | ≥50 | 164.4 (490.6) | 36.5 | ≥50 |
| Coinfection with HW or AL | 966 | 134 | 13.9 (11.7–16.1) | 363.2 (985.5) | 41 | |||
STH: soil-transmitted helminth; CI: confidence interval; HW: hookworms; AL: Ascaris lumbricoides; TT: Trichirus trichiura.