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. 2023 Feb 8;13(2):470. doi: 10.3390/life13020470

Figure 15.

Figure 15

The additive effect of OLE phenolics on GB cell migration capacity of TMZ. TMZ-only, TMZ + OLE, and TMZ + OLE phenolics reduced the cell migration of (A) T98G and (B) A172 cells compared to the TMZ-only treated cells. The edges of the wound area are marked in yellow. The size of the wounded area was initially imaged untreated, then 24 h after treatments with TMZ-only, TMZ + OLE, and TMZ + OLE phenolics at 40× magnification. ImageJ software measured the size of the captured wounded area. p-values were calculated using a dependent sample T-test. Data are shown as mean ± SD. ** p < 0.0001. UNT: untreated, TMZ: temozolomide, OLE: Olea europaea leaf extract, OL: oleuropein, HT: hydroxytyrosol, TYR: tyrosol.