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Effects of compound 1 on Nrf2/HO-1 pathway in LPS-induced RAW264.7 cells. The RAW264.7 cells were pretreated with the compound (5, 10, and 20 μM) for 1h before exposure to LPS for 24 h. The representative blots (A) and the calculated intensities after normalization to α-tubulin (B) were presented. Results are presented as the mean ± standard deviation from three independent experiments. The results differ significantly from LPS-only treated; * p < 0.05, ** p < 0.01, and *** p < 0.001.
