Table 2.
Frequencies of total, fluctuating (ON and OFF), and static non-motor symptoms.
| NMS | Total Frequency NMS (N (%)) | ON NMS | OFF NMS | Static NMS |
|---|---|---|---|---|
| Loss of train of thought | 8 (32.0) | - | - | 8 (32.0) |
| Distraction (difficulty completing task) | 6 (24.0) | 1 (4.0) | - | 5 (20.0) |
| Difficulty planning an activity | 9 (36.0) | 2 (8.0) | 2 (8.0) | 5 (20.0) |
| Confusion | 3 (12.0) | 2 (8.0) | - | 1 (4.0) |
| Word finding difficulty | 14 (56.0) | 3 (12.0) | - | 11 (44.0) |
| Excessive worry | 12 (48.0) | - | 1 (4.0) | 11 (44.0) |
| Fear (feeling scared) | 6 (24.0) | - | 2 (8.0) | 4 (16.0) |
| Restlessness | 14 (56.0) | 1 (4.0) | - | 13 (52.0) |
| Sadness/hopelessness | 13 (52.0) | 2 (8.0) | 2 (8.0) | 9 (36.0) |
| Loneliness/isolation | 4 (16.0) | - | 1 (4.0) | 3 (12.0) |
| Hallucinations | 3 (12.0) | - | - | 3 (12.0) |
| Poor decision making | 1 (4.0) | - | - | 1 (4.0) |
| Impulsiveness | 4 (16.0) | 1 (4.0) | - | 3 (12.0) |
| Compulsions/uncontrollable urges | 5 (20.0) | 1 (4.0) | - | 4 (16.0) |
| Poor short-term memory | 16 (64.0) | 1 (4.0) | - | 15 (60.0) |
| Difficulty handling stressful situations | 3 (12.0) | 1 (4.0) | - | 2 (8.0) |
| Apathy/loss of interest | 8 (32.0) | 3 (12.0) | - | 5 (20.0) |
| Low energy/fatigue | 17 (68.0) | 5 (20.0) | - | 12 (48.0) |
| Excessive daytime sleepiness | 16 (64.0) | 4 (16.0) | 1 (4.0) | 11 (44.0) |
| Pain | 19 (76.0) | 2 (8.0) | 2 (8.0) | 15 (60.0) |
| Altered sensations | 1 (4.0) | 1 (4.0) | - | - |
| Shortness of breath | 7 (28.0) | 1 (4.0) | 1 (4.0) | 5 (20.0) |
| Changes in vision | 7 (28.0) | 1 (4.0) | - | 6 (24.0) |
| Excess sweating | 10 (40.0) | 1 (4.0) | - | 9 (36.0) |
| Palpitations | 1 (4.0) | - | - | 1 (4.0) |
| Urinary symptoms | 18 (72.0) | 3 (12.0) | - | 15 (60.0) |
| Constipation | 14 (56.0) | 1 (4.0) | - | 13 (52.0) |