Figure 1.

Physiology of wound healing. Haemostasis: The immediate response to a surgical injury is the vasoconstriction of blood vessels at the point of injury. Inflammatory process: brings nutrients to the area of surgery, removes debris and bacteria, and provides stimuli for wound repair. Proliferation: involves processes of angiogenesis, granulation tissue production, collagen deposition, and epithelialisation. Remodelling: Type 1 collagen replaces the type 3 collagen found in granulation tissue, and a scar forms.