Figure 1.

Chemical structure, half-cytotoxic concentration (CC₅₀) and IC₅₀ of magnolol (MAG). (A) Chemical structure of MAG. (B) Confluent Vero cell monolayers were cultured for three days in DMEM medium containing two-fold serial dilutions of 100 μM MAG. Cell viability was assessed using the MTT assay, and the CC₅₀ values of MAG were calculated. (C) Confluent Vero cell monolayers were infected with PEDV DR13^att, and treated with two-fold serial dilutions of MAG. After three dpi, the viability of the cells in each group was determined using the MTT assay, and the IC₅₀ value of MAG was calculated. Data are presented as the mean ± SEM of the three independent experiments.