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. 2023 Jan 20;11(2):279. doi: 10.3390/microorganisms11020279

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Bray-Curtis contribution of predictive antimicrobial resistance genes (piARGs) to the overall beta diversity within the categories. The plot shows $N (N - 1) / 2$ pair-wise differences between samples for each category with left set of panels showing organization by antibiotic status whilst right set of panels show organization by smoking status, respectively. “Others” represent the contribution of the remaining KOs that are not identified as potential AMR genes. Higher contributions represent higher intersample variability in terms of piARGs. Lines connecting categories shows significant relationships (Tukey HSD) with * p < 0.05, ** p < 0.01, or *** p < 0.001.