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The post-vaccination antigen-specific cell-mediated immune response in the non-naive CD4+ and CD8+ T-cell populations on days 0, 30, 51, and 90. Cells were considered positive if at least one cytokine out of IFN-γ, IL-2, and TNF-α was expressed. Comparisons were made to day 0 in the corresponding group. p ≤ 0.05 is indicated with *.
