Scheme 2.
General conditions for Ugi: isatin derivative 1–5 (200 mg, 1 equiv), InCl3 (10 mol%), 150 mg of MS 3 Å and methanol (1 mL), n-butylamine (1.5 equiv), isocyanide (1.5 equiv), and carboxylic acid (1.5 equiv), rt.
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