Table 3.
Blue light-induced downregulation of gene expression in human fibroblasts. Shown are significant downregulated genes (≥4×) assessed in blue light-irradiated (20 J/cm2) and non-irradiated human fibroblasts on day 10, with a total of four daily irradiations and 24 h after the last irradiation (n = 4).
| Database Object Name | ID | Fold-Change |
|---|---|---|
| Acyl-CoA-binding domain-containing protein 7 | ACBD7 | −15.59 |
| Leiomodin-1 | LMOD1 | −10.89 |
| Kinesin-like protein KIF20A | KIF20A | −7.23 |
| RP11-867G23.10 | processed_transcript | −6.55 |
| SDPR | protein_coding | −6.53 |
| Serine/threonine-protein kinase Nek2 | NEK2 | −6.50 |
| PICALM interacting mitotic regulator | FAM64A | −6.37 |
| Suppressor APC domain-containing protein 2 | SAPCD2 | −6.04 |
| Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 | ST6GALNAC5 | −6.03 |
| Cell division cycle protein 20 homolog | CDC20 | −5.99 |
| Protein FAM83D | FAM83D | −5.99 |
| Oxytocin receptor | OXTR | −5.94 |
| Tastin | TROAP | −5.67 |
| Serine/threonine-protein kinase PLK1 | PLK1 | −5.51 |
| Histone H3-like centromeric protein A | CENPA | −5.48 |
| Cyclin-dependent kinase inhibitor 3 | CDKN3 | −5.37 |
| Tumor necrosis factor alpha-induced protein 8-like protein 1 |
TNFAIP8L1 | −5.29 |
| Disks large-associated protein 5 | DLGAP5 | −5.25 |
| G2/mitotic-specific cyclin-B1 | CCNB1 | −5.23 |
| G2/mitotic-specific cyclin-B2 | CCNB2 | −5.22 |
| Borealin | CDCA8 | −5.14 |
| Ras GTPase-activating-like protein IQGAP3 | IQGAP3 | −5.09 |
| Centrosomal protein of 55 kDa | CEP55 | −4.99 |
| Lamin-B1 | LMNB1 | −4.98 |
| GAS2-like protein 3 | GAS2L3 | −4.87 |
| Abnormal spindle-like microcephaly-associated protein | ASPM | −4.78 |
| Anillin | ANLN | −4.68 |
| DEP domain-containing protein 1A | DEPDC1 | −4.68 |
| High mobility group protein B2 | HMGB2 | −4.67 |
| Mitotic checkpoint serine/threonine-protein kinase BUB1 | BUB1 | −4.49 |
| Cyclin-A2 | CCNA2 | −4.48 |
| Protein regulator of cytokinesis 1 | PRC1 | −4.44 |
| Matrilin-2 | MATN2 | −4.42 |
| Protein Mis18-beta | OIP5 | −4.32 |
| Kinesin-like protein KIF20B | KIF20B | −4.30 |
| Cyclin-F | CCNF | −4.29 |
| RING finger protein 150 | RNF150 | −4.27 |
| Kinesin-like protein KIF2C | KIF2C | −4.27 |
| Kinetochore scaffold 1 | KNL1 | −4.25 |
| Proline/serine-rich coiled-coil protein 1 | PSRC1 | −4.20 |
| Baculoviral IAP repeat-containing protein 5 | BIRC5 | −4.16 |
| RP11-265N7.1 | lincRNA | −4.14 |
| Proline-rich protein 15 | PRR15 | −4.13 |
| Hyaluronan mediated motility receptor | HMMR | −4.12 |
| Targeting protein for Xklp2 | TPX2 | −4.11 |
| Securin | PTTG1 | −4.09 |
| Cell division cycle-associated protein 3 | CDCA3 | −4.08 |
| Nucleolar and spindle-associated protein 1 | NUSAP1 | −4.05 |