Table 2.

Potential cellular and viral targets of HSV miRNAs ².

Herpesvirus	miRNA	Target	Function	References
Viral targets
HSV-1	miR-H2-3p	ICP0	Immune evasion	[11,46,47]
	miR-H3, miR-H4	ICP34.5	Immune evasion	[9]
	miR-H6	ICP4	Immune evasion	[9]
	miR-H8	GPI	Inhibits viral growth	[44]
HSV-2	miR-I	ICP34.5	Immune evasion	[16,48,49]
	miR-H2	ICP34.5	Immune evasion	[48,49]
	miR-H3/4	ICP0	Immune evasion	[46,48,49]
Cellular targets
HSV-1	miR-H-27	KLHL24	Immune evasion, viral replication and proliferation	[45]

² The table presents HSV-encoded vmiRNAs, their targets (cellular/viral), and their modes of action. Abbreviations: ICP0, infected cell polypeptide 0; ICP34.5, infected cell polypeptide 34.5; ICP4, infected cell polypeptide 4; GPI, glycosylphosphatidylinositol; KLHL24, Kelch-like 24.