Table 3.

Potential cellular and viral targets of HCMV miRNAs ³.

HCMV	miRNA	Target	Function	Reference
Cellular targets	miR-UL112	MICB	Immune evasion	[32]
	miR-US25-2-3p	TIMP3	Immune evasion	[70]
	miR-UL112-3p	TLR2	Immune evasion	[72]
	miRNA UL148D	CCL5	Immune evasion	[73]
	miR-US4-1	ERAP1	Immune evasion	[71]
	miR-US25-1	CD147, CCNE2, EID1, BRCC3, MAPRE2, H3F3B, ATP6V0CP1	Interrupts cell cycle	[11]
	miR-US25-2-3p	eIF4A1	Immune evasion	[74]
Viral targets	miR-UL112-1	IE72, UL114	Favors latency	[75]

³ The table presents HCMV miRNAs, their targets (cellular/viral), and their modes of action. Abbreviations: MICB, MHC class-I-related chain B; TIMP3, tissue inhibitors of metalloprotease 3; TLR2, Toll-like receptor 2; CCL5, chemokine (C-C motif) ligand 5; ERAP1, endoplasmic reticulum aminopeptidase 1; CD147, collagenase stimulatory factor; CCNE2, cyclin E2; EID1, EP300 interacting inhibitor of differentiation 1; BRCC3, BRCA1/BRCA2-containing complex-subunit 3; MAPRE2, microtubule-associated proteins, RP/EB family, member 2; H3F3B, histone proteins; ATP6V0CP1, ATPase-V0 subunit C pseudogene 1 protein; eIF4A1, eukaryotic initiation factor 4A1; IE72, immediate early trans-activator.