Table 1.
Overview of notable clinically used photosensitizers.
| Sensitizer (Brand Name) | Approval | Indication | Wavelength (nm) |
|---|---|---|---|
| 5-aminolevulinic acid/5-ALA (Ameluz) (Levulan) | Worldwide | Mild to moderate actinic keratosis | 635 |
| Bremachlorin (Radachlorin) | Russia, Belarus | Non-small cell lung cancer, bladder, cutaneous lesions | 662 |
| Hexaminolevulinate hydrochloride (Cysview) | Europe, USA, Canada | Bladder cancer detection | 360–450 |
| Methyl aminolevulinate (Metvix) (Metvixia) | Worldwide | Non-hyperkeratotic actinic keratosis and basal cell carcinoma | 570–670 |
| Porfimer sodium (Photofrin) | Worldwide | Esophageal cancer, Barrett’s Esophagus, non-small cell lung cancer | 630 |
| Redaporfin (LUZ11) | Orphan status in Europe | Biliary tract cancer | 749 |
| Synthetic hypericin (SGX301) | Orphan status in Europe, conditional FDA | Early-stage cutaneous T-cell lymphoma | 570–650 |
| Talaporfin sodium/NPe6 (Laserphyrin) | Japan | Lung cancer | 664 |
| Temoporfin/mTHPC (Foscan) | Europe | Advanced Head and neck cancer | 652 |
| Verteporfin (Visudyne) | Worldwide | Age-related macular degeneration | 690 |
| WST-11/padeliporfin (TOOKAD) | Europe | Prostatic Neoplasms | 753 |