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. 2023 Feb 16;24(4):4012. doi: 10.3390/ijms24044012

Figure 1.

Figure 1

(A) Time course of the ROS production rate (μmol·min−1) assessed by EPR technique and (B) SpO2 (%) during the transition from normoxia to acute normobaric hypoxia and back to normoxia during recovery. EXP group: full symbols are the data obtained before (0 min) and 15, 30, 45 min after hypoxia exposure (recovery); open symbols are the data during hypoxia status: at 5, 15, 30, 60, 120, 180, 240 min. Green symbols are the data obtained from the CTR (room air, normoxia state FiO2 = 0.21) for ROS (μmol·min−1) and SpO2 (%). In the inset at the right bottom of Figure A, the exponential fit of the on-transient kinetics data (t1/2 = 30.02 min, r2 = 0.995) is shown. Results are expressed as mean ± SD. (C) Data (full symbols) and linear correlation line (continuous line, r = 0.43) of the ROS production rate versus SpO2. Changes over time were significantly different when compared to pre-exposure levels (* p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001 symbols).