Figure 7.
Effects of RRP15 knockdown or overexpression on epithelial-mesenchymal transition (EMT) of CC cells. (A) Representative images of IHC staining of RRP15, E-cadherin and N-cadherin in CC tissues and paired adjacent tissues (scale bar = 100 μm). (B) Effects of RRP15 knockdown on the expression of E-cadherin in HCT15 cells examined by Western blot. Representative blots via densitometry. (C) Effects of RRP15 knockdown on the expression of N-cadherin in HCT15 cells via Western blot. Representative blots are shown with densitometry (n = 3). (D) The effect of RRP15 overexpression on expression of E-cadherin in HCT116 cells was examined by Western blot. Representative blots are shown with densitometry. (E) Effects of RRP15 overexpression on the N-cadherin expression in HCT116 cells by Western blot. Representative blots showed under densitometry. * p < 0.05 and ** p < 0.01 versus the control shRNA group; # p < 0.05 and ## p < 0.01 versus the control vector group, n = 3.
