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. 2023 Jan 27;13(2):221. doi: 10.3390/jpm13020221

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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PD-L1, CD4, and CD8 tumor-infiltrating lymphocytes expressions patterns as potential biomarkers in melanoma diagnosis. Receiver operating curve (ROC) analyses were generated from 61 patients and had a value of the area under the curve (AUC) for PD-L1 (TILs: sensitivity: 97.30%, specificity: 91.67%; p < 0.001; M: sensitivity: 96.43%, specificity: 96.97%; p < 0.001), CD8 tumor-infiltrating lymphocytes (M: sensitivity: 89.13%, specificity: 86.67%; p < 0.001), and CD4 tumor-infiltrating lymphocytes (M: sensitivity: 84.31%, specificity: 90.00%; p < 0.001), respectively.