. 2023 Jan 27;13(2):221. doi: 10.3390/jpm13020221

Table 4.

Logistic regression of potential prognostic values of PD-L1, CD4, and CD8 TILs in melanoma tumor microenvironment cells.

Nb.	Clinical Variables	Multivariate Analysis
		Melanoma Tumor Microenvironment Cells
		Hazard Ratio	p-Value	95% CI *
1.	Lymphovascular invasion	3.049	0.528	0.095−97.914
2.	Perineural invasion	0.026 *	*0.023*	0.001−0.607
3.	PD-L1	2.700	0.455	0.198−36.683
4.	CD4 TILs	11.838 *	*0.023*	1.386−101.108
5.	CD8 TILs	7.748 *	*0.018*	1.408−42.622

CI^∗- Confidence interval; * p < 0.05 represents statistically significant differences between variables made by Cox Logistic & Snell regression (Cox & Snell R²). PDL-1 in MTC-R² = 0.23, p = 0.43; CD8 TILs in MTC – R² = 0.49, p < 0.0001; CD4 TILs in MTC - R² = 0.38, p = 0.002.