Table 1.
FDA-approved drugs to improve cognitive functions.
| Drug | Structure | Therapeutic Effects |
|---|---|---|
| Donepezil |
|
selectively and reversibly inhibits cholinesterase, improves the cognitive and behavioral signs and symptoms of AD, neuroprotective |
| Galantamine |
|
levels decrease as the disease progresses, not considered as a disease-modifying drug |
| Rivastigmine |
|
parasympathomimetic and a reversible cholinesterase inhibitor, enhancing cholinergic function |
| Memantine |
|
inhibits calcium influx into cells, enhances neuronal synaptic plasticity |