Table 5.
Half-maximal inhibition concentration (IC50, μg/mL) of propolis against human carbonic anhydrase isoenzyme II (hCA II) acetylcholinesterase (AChE), and α-glycosidase (α-Gly) enzymes.
| Antioxidants | hCA II | AChE | α-Glycosidase | |||
|---|---|---|---|---|---|---|
| IC50 | r2 | IC50 | r2 | IC50 | r2 | |
| Propolis | 19.6 | 0.9327 | 3.4 | 0.9869 | 3.7 | 0.9362 |
| Acetazolamide * | 8.37 | 0.9825 | - | - | - | - |
| Tacrine ** | - | - | 5.97 | 0.9706 | - | - |
| Acarbose *** | - | - | - | - | 22,800 | - |
*Acetazolamide was used as standard inhibitor for hCA, ** Tacrine was used as standard inhibitor for AChE, *** Acarbose was as used standard inhibitor for α-glycosidase, which was obtained from the literature [50].