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Maximum inhibitory effect (at the highest concentration used, expressed as a percentage) of favilipid A (1) on kinase activities and corresponding IC50 values (concentrations eliciting 50% of the maximum response) with 95% confidence intervals (CI).
| Kinase | % Inhibition | IC50 (μM) | 95% CI (μM) |
|---|---|---|---|
| JAK3 | 58% | 3.5 | 2.0–5.9 |
| IKKβ | 54% | 6.0 | 1.4–77.8 |
| SYK | 48% | 8.3 | 4.9–13.8 |
| PKCα | 40% | 3.3 | 2.1–5.0 |
| FGFR1 | 38% | 10.7 | 8.8–12.9 |
