Table 1.

An overview of what to expect when setting up a screening to find (novel) antifungals.

	Natural Products		Synthetic Compounds
	Fungi-Derived	Bacteria-Derived
Most common hits	B-glucan synthase inhibitors (12% of hits) [50]	Polyenes (95% of hits) [47]	Azoles (15% of hits) [50]
Hit rates (%)	~20% [50]	~9% [50]	~0.1–2% [51,52,53]
Common PAINs	Mycotoxins [50]	Ionophores [50]	Rhodanines [54]