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. 2023 Feb 17;11(2):189. doi: 10.3390/toxics11020189

Table 4.

Local priority for each criterion and global priority of the protein targets (alternatives). The Criteria priority vector is shown in bold.

Protein Local Priority Global Priority
Position in Ft (Solubility Alteration) Ranking Position in Fc p-Value Ranking Number of Diseases Where It Is Involved Number of Reported Negative Effects on Cells/Organs/Organisms When Functionality Is Absent Relevance of Reported Negative Effects on Cells/Organs/Organisms When Functionality Is Absent Number of Pathways Where It Has Participation Relevance of Pathways Where It Has Participation Number of Functional and Physical Protein Associations with Other Protein Targets
0.258 0.258 0.060 0.061 0.166 0.044 0.133 0.021
GTF3C4 0.093 0.130 0.006 0.006 0.016 0.004 0.008 0.002 0.265
FAM98B 0.067 0.019 0.006 0.006 0.016 0.004 0.015 0.002 0.135
HSPB1 0.048 0.064 0.058 0.052 0.118 0.035 0.037 0.002 0.414
RAB1A 0.035 0.047 0.006 0.022 0.062 0.035 0.037 0.019 0.264
MTPN 0.024 0.103 0.006 0.006 0.016 0.001 0.002 0.010 0.168
KIAA0368 0.016 0.082 0.006 0.011 0.016 0.000 0.001 0.010 0.142
GRHPR 0.010 0.011 0.042 0.018 0.149 0.004 0.055 0.002 0.291
CNPY3 0.007 0.035 0.042 0.018 0.149 0.004 0.041 0.002 0.297