. Author manuscript; available in PMC: 2023 Feb 25.

Published in final edited form as: Asia Pac J Ophthalmol (Phila). 2022 Aug 30;11(4):314–327. doi: 10.1097/APO.0000000000000538

TABLE 3.

Summary of Post-Transplantation Tests

Categories	Methods	Examined Features	In Vivo	References
Behavior tests	SAS	Light-dark discrimination	Yes	21,35,41
	SAS	Light threshold (shock)	Yes	21,35,41
	Light-avoidance test	Light-dark discrimination	Yes	39
	OKT	Visual acuity	Yes	16,19,45
	OKT	Contrast sensitivity	Yes	16,19,45
Electrophysiology	VGS	Eye movement: latency, amplitude, and peak velocity	Yes	43
	ERG	Electrical activity of retina in response to light stimulation	Yes	19
	MEA-based mERG (micro-ERG)	Local electrical potential changes evoked by light	No	41,40,43,37
	SC recording	Spike counts after light stimulus (different light intensity)	Yes	16,19,45
	SC recording	Correlate visual responses in SC to certain retinal areas	Yes	16,19,45
Graft differentiation, integration and synaptogenesis	SDOCT	Location and overview of transplant	Yes	16,19,45
	SDOCT	Graft thickness	Yes	16,19,45
	FAOSLO	Survival, migration, and neurite outgrowth of fluorescent labeled transplant cells	Yes	38
	IHC	Labels specific proteins in tissue to reveal certain cell types, synapses and the overall structure of transplant and host	No	Almost all transplantation research projects applied this technique

ERG indicates electroretinogram; FAOSLO, fluorescence adaptive optics scanning light ophthalmoscopy; IHC, Immunohistochemistry; MEA, microelectrode array; OKT, optokinetic test; SAS, shuttle-avoidance system; SC, superior colliculus; SDOCT, spectral-domain optical coherence tomography; VGS, visually guided saccades.