Figure 10.

Evaluation of changes in human Wharton’s jelly mesenchymal stem cells (hWJ-MSCs) viscoelasticity during the treatment with different concentrations of Cytochalasin B (CB) using Ting’s model. (a) Time-wise behavior for the representative Young’s modulus (E₀) and power-law exponent (α) values in the untreated (CTR) and CB-treated cells (0.1, 1, and 3 μM). The continuous lines are guides for the eye. Images are representative stiffness (b) and viscosity (c) maps of single untreated (CTR) or treated cells with CB at 0.1, 1, and 3 μM. Each point in a map refers to a specific value of the Young’s modulus (E₀) or of the power-law exponent (α) and refers to a false color scale. The color scale is shown to the right of each row. The white regions around the cell represent the substrate (the white dots within the cell regions are due to individual force curves that have been discarded due to poor quality). Scale bars: 20 μm.